The Global ODEs and DAEs interface (), found under the Mathematics branch () when adding a physics interface, is used to add global space-independent equations that can represent additional states. The equations can be ODEs, algebraic equations, and DAEs. The main default node is Global Equations, used to define the global equations including the names of the variables (states), the required initial values, and an optional description.

The following nodes are available from the Global ODEs and DAEs ribbon toolbar (Windows users), Global ODEs and DAEs context menu (Mac or Linux users), or by right-clicking to access the context menu (all users).